Adenophora Extract Powder(Sha Shen)10:1, 20:1, 50:1 TLC
Adenophora extract has the effects of clearing heat and moistening the lungs, tonifying qi and strengthening the spleen, nourishing yin and generating fluids, reducing fire and stopping blood, calming the mind and calming the mind. It is mainly used to treat symptoms such as lung heat cough, dry cough without phlegm, and spleen deficiency and loss of appetite.
Adenophora Extract Powder(Sha Shen)10:1, 20:1, 50:1 TLC
【Botanical source】: Adenophora stricta Miq., Adenophora hunanensis Nannf., Adenophora tetraphylla (Thunb.) Fisch.[A.vuerticillata Fisch.;Campanula tetraphylla Thunb.], Adenophora khasiana(Hook.fF.et Thoms.)Coll.et Hhemsl [Caumpanula khasiana Hook.f.et Thoms]
【Extraction source】: The dried roots of several species of plants in the family Campanulaceae, including Adenophora stricta Miq., Adenophora hunanensis Nannf., Adenophora tetraphylla (Thunb.) Fisch.[A.vuerticillata Fisch.;Campanula tetraphylla Thunb.], Adenophora khasiana(Hook.fF.et Thoms.)Coll.et Hhemsl [Caumpanula khasiana Hook.f.et Thoms], Adenophora potaninii Korsh. Adenophora stricta is distributed in Jiangsu, Anhui, Zhejiang, Jiangxi, Hunan and other places; Adenophora hunanensis is distributed in Hebei, Shanxi, Shaanxi, Jiangxi, Henan, Hubei, Hunan, Guangdong, Guangxi, Sichuan, Guizhou and other places; Adenophora tetraphylla is distributed in Northeast, North China, East China, Southwest, and South China; Adenophora khasiana is distributed in Sichuan, Yunnan and Xizang; Adenophora potaninii is distributed in Shanxi, Shaanxi, Ningxia, Gansu, Qinghai, Sichuan and other places.
【Functions in TCM】: Nourishing yin and clearing heat; Moisturizing the lungs and resolving phlegm; Benefiting the stomach and generating fluids. Long cough due to yin deficiency; Phlegm and blood caused by tuberculosis and cough; Dry cough and less phlegm; Deficiency heat throat obstruction; Tianjin hurts thirst.
【Specification】: 10:1, 20:1, 50:1 TLC
【Appearance】: Brownish yellow powder
【Particle size】: 95% pass 80 mesh size
Adenophora Extract(Sha Shen) Production Flowchart
Adenophora raw materials – natural air drying–Coarse powder(40 mesh) -Low temperature water extraction – 1st Reflux Extraction(10 times water,2 Hrs) – 2nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators – warehousing
Specification of Adenophora Extract(Sha Shen)
| Item | Standard | Test method |
| Appearance | Brownish Yellow fine powder | Visual & Organoleptic |
| Specification | 10:1 | TLC |
| Particle size | 80 mesh | Pass 80 mesh size screen |
| Ash | <13% | 2g/525℃/3hrs |
| Moisture | <7% | 5g/100℃/2.5hrs |
| Heavy metals | As <1.0ppm Pb<2.0PPM Hg<0.2ppm Cd<1.0ppm | Atomic Absorption |
| Microbiological Control | Total Plate Count<10,000cfu/g, Yeast & Mold<100cfu/g, E.Coli<10cfu/g. |
AOAC |
| Packing | 1kg/bag, 5kg/bag, or 25kg/fiber drum (D* H, 40*50cm),
It can also be packaged according to the requirements of customers, and all the packaging materials meet the standards of Chinese Pharmacopoeia 2010. |
|
Extended Reading
Chemical Composition of Adenophora (Sha Shen)
Four compounds were isolated from the roots of Salvia miltiorrhiza, which are β-sitosterol，β-sitosterol-O-β-D-glucopyranoside，taraxerone，octa-cosanoic acid.
Pharmacological effects of Adenophora (Sha Shen)
1.Impact on immune function
Intraperitoneal injection of Adenophora hunanensis decoction (0.5g per mouse) can significantly increase the number of lymphocytes and T cells in the peripheral blood of mice; The number of lymphocytes and T cells in the thymus also showed an increasing trend, which significantly increased the phagocytic percentage of mouse peritoneal macrophages; It can significantly increase the weight of mouse spleen, but reduce the number of lymphocytes and T cells in mouse spleen. Indicating that sand ginseng can enhance cellular and non-specific immunity in the body, and inhibit humoral immunity. It has the function of regulating immune balance. Sha Shen can also increase the lymphocyte conversion rate.
2. Expectorant effect
The administration of Sha Shen decoction to rabbits at a dose of 1g/kg indicates a certain expectorant effect, which can last for more than 4 hours. However, the intensity of the effect is not as strong as that of purple flowers.
3. Antifungal effects
Sha Shen water extract (1:2) has varying degrees of inhibitory effects on skin fungi such as Clostridium oxysporum and Clostridium woolly in vitro. 1% Sha Shen infusion has a significant cardiotonic effect on the isolated heart of toads, with an increased amplitude of the isolated heart and a sustained effect lasting for 5 minutes.